The Anti-Hu CD274 FITC Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD274. This antibody recognizes Human, and Non-Human Primate antigen. The Anti-Hu CD274 FITC Antibody has been validated for the following applications: Flow Cytometry.
Description
CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its ligand CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely